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1

Lead compounds discovered from libraries

Adam Golebiowski, Sean R Klopfenstein, David E Portlock

Journal:

Current Opinion in Chemical Biology

Year:

2001

Language:

english

File:

PDF, 223 KB

english, 2001

2

The universal Rink-isonitrile resin: applications in Ugi reactions

Jack J Chen, Adam Golebiowski, Sean R Klopfenstein, Laura West

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 98 KB

english, 2002

3

A traceless linker approach to the solid phase synthesis of substituted guanidines utilizing a novel acyl isothiocyanate resin

Lawrence J. Wilson, Sean R. Klopfenstein, Min Li

Journal:

Tetrahedron Letters

Year:

1999

Language:

english

File:

PDF, 236 KB

english, 1999

4

Aminomethyl tetrahydronaphthalene biphenyl carboxamide MCH-R1 antagonists—Increasing selectivity over hERG

Kenneth M. Meyers, Nicholas Kim, José L. Méndez-Andino, X. Eric Hu, Rashid N. Mumin, Sean R. Klopfenstein, John A. Wos, Maria C. Mitchell, Jennifer L. Paris, David C. Ackley, Jerry K. Holbert, Scott W

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 155 KB

english, 2007

5

1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors

Sean R. Klopfenstein, Artem G. Evdokimov, Anny-Odile Colson, Neil T. Fairweather, Jeffrey J. Neuman, Matthew B. Maier, Jeffrey L. Gray, Gina S. Gerwe, George E. Stake, Brian W. Howard, Julie A. Farmer

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 237 KB

english, 2006

6

Solid-Supported Synthesis of a Peptide β-Turn Mimetic

Golebiowski, Adam, Klopfenstein, Sean R., Shao, Xia, Chen, Jack J., Colson, Anny-Odile, Grieb, Arthur L., Russell, Anne F.

Journal:

Organic Letters

Year:

2000

Language:

english

File:

PDF, 63 KB

english, 2000

7

A practical synthesis of peptide mimetics via the solid-phase Petasis reaction

Sean R Klopfenstein, Jack J Chen, Adam Golebiowski, Min Li, Sean X Peng, Xia Shao

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 152 KB

english, 2000

8

Solid supported synthesis of hydroxamic acids

Adam Golebiowski, Sean Klopfenstein

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 185 KB

english, 1998

9

Lead compounds discovered from libraries: Part 2

Adam Golebiowski, Sean R Klopfenstein, David E Portlock

Journal:

Current Opinion in Chemical Biology

Year:

2003

Language:

english

File:

PDF, 325 KB

english, 2003

10

A novel method for the efficient synthesis of 2-arylamino-2-imidazolines

Sreenivasa R Mundla, Larry J Wilson, Sean R Klopfenstein, William L. Seibel, Nick N Nikolaides

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 159 KB

english, 2000

11

ChemInform Abstract: High-Throughput Organic Synthesis of Peptide Mimetics.

Adam Golebiowski, Sean R. Klopfenstein, David E. Portlock

Journal:

Year:

2002

File:

PDF, 25 KB

2002

12

Solid-Supported Synthesis of Putative Peptide β-Turn Mimetics via Ugi Reaction for Diketopiperazine Formation

Golebiowski, Adam, Jozwik, Julita, Klopfenstein, Sean R., Colson, Anny-Odile, Grieb, Arthur L., Russell, Anne F., Rastogi, Vinit L., Diven, Conrad F., Portlock, David E., Chen, Jack J.

Journal:

Journal of Combinatorial Chemistry

Year:

2002

Language:

english

File:

PDF, 138 KB

english, 2002

13

Automated High-Throughput Liquid−Liquid Extraction for Initial Purification of Combinatorial Libraries

Peng, Sean X., Henson, Charles, Strojnowski, Michael J., Golebiowski, Adam, Klopfenstein, Sean R.

Journal:

Analytical Chemistry

Year:

2000

Language:

english

File:

PDF, 80 KB

english, 2000

14

The reactions of [Pd 2 Cl 2 (μ-PP) 2 ] (PP = dppm, dmpm) with Et 2 NC≡CNEt 2 in methylene chloride solution: X-ray crystal structures of [Pd 2 Cl 2 (μ-CH 2 )(μ-dppm) 2 ] and hexakis(diethylamino)benzene, C 6 (NEt 2 ) 6

Klopfenstein, Sean R., Kluwe, Constanze, Kirschbaum, Kristin, Davies, Julian A.

Journal:

Canadian Journal of Chemistry

Year:

1996

Language:

english

File:

PDF, 567 KB

english, 1996

15

Solid supported high-throughput organic synthesis of peptide β-turn mimetics via tandem Petasis reaction/diketopiperazine formation

Adam Golebiowski, Sean R Klopfenstein, Jack J Chen, Xia Shao

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 128 KB

english, 2000

16

ChemInform Abstract: A Novel Method for the Efficient Synthesis of 2-Arylamino-2-imidazolines.

Sreenivasa R. Mundla, Larry J. Wilson, Sean R. Klopfenstein, William L. Seibel, Nick N. Nikolaides

Journal:

Year:

2000

File:

PDF, 30 KB

2000

17

Universal Rink–isonitrile resin: application for the traceless synthesis of 3-acylamino imidazo[1,2-a]pyridines

Jack J Chen, Adam Golebiowski, Joel McClenaghan, Sean R Klopfenstein, Laura West

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 97 KB

english, 2001

18

Multi-Component Synthesis of Imidazo[1,2-a] Annulated Heterocycles on α-Isocyano Resin Esters

Chen, Jack J., Golebiowski, Adam, Klopfenstein, Sean R, McClenaghan, Joel, Peng, Sean X., Portlock, David E., West, Laura

Journal:

Year:

2001

Language:

english

File:

PDF, 76 KB

english, 2001

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